E Dale Abel Selected Research

Facilitative Glucose Transport Proteins (Glucose Transporter)

1/2022	The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming.
1/2021	GLUT1 Expression in Tumor-Associated Neutrophils Promotes Lung Cancer Growth and Resistance to Radiotherapy.
1/2020	Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth.
11/2018	Glucose metabolism induced by Bmp signaling is essential for murine skeletal development.
12/2017	Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.
12/2016	The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.
9/2013	Inducible overexpression of GLUT1 prevents mitochondrial dysfunction and attenuates structural remodeling in pressure overload but does not prevent left ventricular dysfunction.
3/2013	Absence of glucose transporter 4 diminishes electrical activity of mouse hearts during hypoxia.
2/2012	Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice.
1/2011	Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.

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E Dale Abel Research Topics

Disease

26	Obesity 01/2021 - 12/2004
22	Insulin Resistance 12/2017 - 06/2005
21	Hypertrophy 11/2021 - 01/2004
19	Cardiomegaly (Heart Hypertrophy) 11/2021 - 06/2006
16	Heart Failure 10/2021 - 06/2006
16	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 03/2008
13	Type 2 Diabetes Mellitus (MODY) 01/2019 - 06/2005
11	Ischemia 01/2020 - 01/2004
8	Neoplasms (Cancer) 01/2021 - 03/2008
7	Fibrosis (Cirrhosis) 11/2021 - 08/2010
7	Hyperglycemia 10/2020 - 12/2005
6	Cardiomyopathies (Cardiomyopathy) 01/2022 - 07/2008
5	Diabetic Cardiomyopathies 11/2021 - 11/2011
5	Hypertension (High Blood Pressure) 01/2021 - 05/2009
5	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019 - 09/2009
4	Inflammation (Inflammations) 11/2019 - 03/2012
4	Diabetes Mellitus 01/2019 - 07/2010
4	Hyperinsulinism (Hyperinsulinemia) 12/2017 - 09/2004
4	Hypoxia (Hypoxemia) 03/2013 - 11/2004
3	Ventricular Remodeling 01/2021 - 04/2016
3	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2021 - 01/2017
3	Glucose Intolerance 08/2015 - 08/2008
3	Morbid Obesity 08/2015 - 10/2008
3	Body Weight (Weight, Body) 05/2011 - 12/2009
3	Iron Overload 01/2011 - 03/2008
2	Adenocarcinoma of Lung 01/2021 - 01/2020
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021 - 05/2010
2	Lung Injury 10/2020 - 11/2019
2	Reperfusion Injury 01/2020 - 07/2015
2	Thrombosis (Thrombus) 01/2019 - 01/2017
2	Pulmonary Embolism 01/2019 - 01/2017
2	Albuminuria 01/2018 - 02/2014
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018 - 02/2014
2	Weight Gain 05/2017 - 01/2017
2	Breast Neoplasms (Breast Cancer) 12/2016 - 01/2011
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2016 - 08/2015
2	Left Ventricular Dysfunction 01/2011 - 06/2009
2	Hemochromatosis (Bronze Diabetes) 01/2011 - 03/2008
1	Encephalomyelitis (Myeloencephalitis) 01/2022
1	Colitis 01/2022
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 11/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Atrophy 01/2021
1	Glut1 Deficiency Syndrome 01/2021

Drug/Important Bio-Agent (IBA)

38	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2004
34	Insulin (Novolin)FDA Link 01/2021 - 01/2004
17	Fatty Acids (Saturated Fatty Acids)IBA 11/2021 - 09/2004
13	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2006
10	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2022 - 01/2011
8	Adenosine Triphosphate (ATP)IBA 01/2018 - 01/2004
8	LipidsIBA 01/2018 - 08/2008
7	Insulin ReceptorIBA 01/2021 - 06/2006
6	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2021 - 11/2008
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 09/2008
4	CollagenIBA 11/2021 - 01/2017
4	CalpainIBA 10/2021 - 11/2011
4	AntioxidantsIBA 01/2020 - 02/2012
4	Phosphotransferases (Kinase)IBA 01/2019 - 09/2012
4	Nonesterified Fatty Acids (NEFA)IBA 03/2012 - 05/2009
3	Protein Isoforms (Isoforms)IBA 11/2021 - 06/2006
3	fibroblast growth factor 21IBA 01/2021 - 01/2017
3	Insulin-Like Growth Factor I (IGF-1)IBA 01/2021 - 11/2008
3	CeramidesIBA 11/2015 - 10/2008
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2013 - 10/2007
3	IronIBA 01/2011 - 03/2008
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2021 - 12/2017
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2021
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2021 - 12/2015
2	CytokinesIBA 01/2019 - 03/2013
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2019 - 01/2017
2	ReninIBA 01/2019 - 01/2018
2	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2017 - 11/2015
2	Oxygen (Dioxygen)IBA 01/2017 - 07/2010
2	CalciumIBA 01/2017 - 08/2008
2	Cre recombinaseIBA 12/2016 - 06/2006
2	Pyruvic Acid (Pyruvate)IBA 10/2016 - 03/2009
2	Superoxides (Superoxide)IBA 01/2016 - 11/2007
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 11/2015 - 05/2009
2	manganese(III)-tetrakis(4-benzoic acid)porphyrinIBA 08/2015 - 02/2012
2	Mitochondrial Uncoupling ProteinsIBA 08/2015 - 10/2007
2	AdiponectinIBA 01/2015 - 09/2008
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 08/2014 - 12/2007
2	TOR Serine-Threonine KinasesIBA 02/2014 - 12/2009
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2014 - 01/2013
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2013 - 01/2011
2	Adenosine Diphosphate (ADP)IBA 01/2013 - 09/2008
2	EnzymesIBA 02/2012 - 08/2008
2	ProteomeIBA 05/2011 - 09/2009
2	Captopril (Capoten)FDA LinkGeneric 08/2008 - 06/2006
2	AdipokinesIBA 04/2008 - 09/2005
2	PPAR alphaIBA 06/2006 - 11/2004
1	Coconut OilIBA 11/2021
1	Matrix Metalloproteinases (MMPs)IBA 11/2021
1	Unsaturated FatsIBA 11/2021
1	Dietary Fats (Dietary Fat)IBA 11/2021
1	lardIBA 11/2021
1	G-Protein-Coupled Receptor Kinase 2IBA 11/2021
1	Recombinases (Recombinase)IBA 01/2021

Therapy/Procedure

2	Therapeutics 01/2019 - 02/2012
1	Radiotherapy 01/2021